Dining out is seldom about all of the pomp and circumstance of a pressed cloth table covering or a formal place setting and fine wine – although there is a time and a place for that kind of meal, too. Most of the time when we eat out, we just want a great dining experience that includes a casual atmosphere, friendly staff, and delectable food. But there is still another scenario: it involves that rare occasion when you’re willing to give in to your hearty appetite and order copious amounts of food, so much that you’ll never be able to eat it all in one sitting. We love it when we find a hidden gem like this, and that’s exactly what we found in the small town of Darlington. Mayflower Seafood Restaurant, a small southern chain, has one of its best outposts here, and the menu is simple but delicious, It specializes in crispy-fried seafood that feels like it was just plucked from the sea. Read on to discover why this iconic seafood joint has stood the test of time and is always packed with locals.

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Even if your eyes are considerably bigger than your stomach, Mayflower Seafood Restaurant is a wonderful choice because you’ll have leftovers that will surely heat up nicely for another meal! Ready to check it out? Or have you already found the goodness here? Let us know!

Mayflower Seafood Restaurant is currently open seven days a week. Make sure to follow this Darlington seafood restaurant on Facebook for any updates.

If you’re visiting Darlington and don’t think you’ll be up for a long drive after this mighty seafood feast, consider checking into the Hilton Garden Inn Florence, which is only a 20-minute drive from the restaurant. Can’t quite make it all the way to Darlington in time to satisfy your seafood craving this time around? Check out this seafood bucket list with restaurants scattered along the South Carolina coast!

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More to Explore

South Carolina Seafood Gems

What Are The Best Seafood Restaurants In South Carolina?

Mayflower Seafood Restaurant is just one of the gems hiding in the state, as we have an amazing seafood culture thanks to the coastline.

  • Flowers Seafood in Edisto Island might be the best spot for fresh seafood - and we mean really fresh! The bounty of the sea here is served straight from the boat, and the business does most of its sales in fresh seafood at the market. But it also serves a simple menu from an attached fish shack, with the specialty being fried shrimp that come with a side of crispy hush puppies. If you're in town for soft-shell crab season, don't miss this specialty - you can devour it in the attached picnic shed.
  • Hook and Barrel is one of those sprawling seafood restaurants that dot Myrtle Beach, serving some of the state's top seafood in a nautical-themed environment. The menu is spectacular, with starters like bourbon hanging bacon and a massive skillet chocolate chip cookie for dessert. But if there's one buzz-worthy dish here that's a must-get, it's the huge seafood tower. It's packed with shrimp, crab, and lobster, served simply steamed and chilled for the purest seafood taste possible.
  • Bubba's Fish Shack, hiding in Surfside Beach, has the aesthetic of an old-school country restaurant, and the interior is a quirky spot with hanging decor. Don't let the informal appearance fool you, though - this place knows its food. Start with the hush puppies for an appetizer - perfect for sharing - before moving on to a massive Captain's Platter with grilled shrimp, flounder, catfish, and bay scallops plus fries, coleslaw, and more of those delicious hush puppies!

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