A road trip through Missouri, no matter where it leads, pretty much guarantees a ton of fun and happy memories. From natural wonders and waterfalls to small towns and leaf peeping, there’s a road trip in Missouri for everyone. Next time wanderlust strikes, pack up and pile your whole family in the car, and hit the road. Here are just a few of the best road trips in Missouri to get you going.

1-Day Road Trip In Missouri

3-Day Weekend Road Trip In Missouri

Missouri Ozarks Road Trip

Weston Road Trip

Best Missouri Road Trip For Spring

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Best Waterfalls in Missouri: 14 Local Favorites & Hidden Gems

Best Summer Road Trip In Missouri

Best Missouri Road Trip For Fall

Best Winter Road Trip In Missouri

Family Friendly Missouri Road Trip

Road Trip to Missouri Landmarks & Natural Wonders

Road Trip to Best Small Towns in Missouri

For road trip planning and packing tips, check out OnlyInYourState’s Ultimate Road Trip Packing List. Whether you’re leaving for a single day or a week-long road trip, you can’t forget the snacks: here are 50 on-the-go snack ideas perfect for traveling.

Have these road trips through Missouri kicked up your wanderlust? What’s your favorite Missouri road trip itinerary? Let us know in the comments! If you’re up for more road-tripping, set off on this road trip to Missouri’s best caves and waterfalls.

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Visiting Missouri

What are the most popular landmarks to visit in Missouri?

A visit to the Show-Me State wouldn't be complete without stopping by some of the most popular landmarks in Missouri, including:

  • The Gateway Arch. Check out the museum at the base before taking a ride to the top for the most spectacular views of St. Louis.
  • Mark Twain Boyhood Home & Museum. Hannibal, the charming small town where Mark Twain grew up, is all about the beloved American author.
  • Meramec Caverns. Historic caverns that date back more than 400 million years, this popular attraction in Missouri offers 1.5-hour tours.


What are the most popular state parks to visit in Missouri?

Outdoor lovers have no shortage of state parks to visit in Missouri. Of the 92 state parks and historic sites, here are some of the most popular state parks in Missouri:

  • Roaring River State Park
  • Bennett Spring State Park
  • Castlewood State Park
  • Cuivre River State Park
  • Taum Sauk Mountain State Park
  • Johnson's Shut-Ins State Park
  • Elephant Rocks State Park


What are the major highways in Missouri?

Major highways in Missouri include:

  • I-29
  • I-35
  • I-44
  • I-64
  • I-70