As local travel experts, we know what travelers are looking for when it comes to finding the perfect accommodations for their next trip. To compile our lists, we scour the internet to find properties with excellent ratings and reviews, desirable amenities, nearby attractions, and that something special that makes a destination worthy of traveling for.

Mississippi is full of Southern charm, natural beauty, rich history, and delicious food. There’s nothing like a country drive or some fresh Gulf Coast seafood. Whether you’re taking a steamboat tour of the Mississippi River or enjoying the beauty of the Gulf of Mexico, you’ll love exploring this beautiful state. When the day’s exploring is done, it’s always a good feeling to rest up at a clean, comforting, lovely hotel which will make your trip well worth remembering. Here are 12 of the best hotels and resorts in Mississippi that provide amazing places to stay.

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Best Unique Hotels To Stay In Mississippi

Picking the nicest hotels in Mississippi can be a challenge, so many will opt for the tried and true accommodations found at a hotel chain like Hilton, Wyndham, or Marriott. However, sometimes you want something different that provides a singular experience. To help get you started in your search, here are some unique, top-rated hotels in Mississippi.

1. Hotel Chester
Management/TripAdvisor
101 N Jackson St, Starkville, MS 39759, USA
Faithruggiero1/TripAdvisor
Hotel Chester in historic downtown Starkville has won several awards for being a charming, inviting hotel. It’s filled with quaint, old-fashioned furnishings in the hotel rooms that will take you back in time. At night, the outdoor patio area is softly lit with strings of lights that resemble fireflies. There are beautiful gardens and comfortable beds, and the service is so friendly.

  • Address: 101 N Jackson St, Starkville, MS 39759
  • Price: From $104/night
  • Amenities: Free Parking, Bar/Lounge, Free Wi-fi, Shuttle service, Shops, Dry cleaning, Blackout curtains, Desk, Coffee maker, Extra long beds, Air conditioning, Interconnected rooms available, Flatscreen TV, Private bathroom
  • Rating: 4.5 stars
2. Shack Up Inn
Douglas Thorn/Google
1 Commissary Cir Rd, Clarksdale, MS 38614, USA
Barbro K/Trip Advisor
Don’t let the exterior fool you, the interior may be rustic, but it’s clean, safe, and cozy. The Shack Up Inn is a collection of old sharecropper cabins in Clarksdale that have been fully restored and the place is dedicated to the history of Mississippi Delta Blues. The cabins are full of antiques and each one is completely unique. The on-site restaurant is packed with signs, lights, and objects from decades past as well as delicious and comforting Southern fare. You’ll end up taking hundreds of photos.

  • Address: 1 Commissary Cir, Clarksdale, MS 38614
  • Price: From $80/night
  • Amenities: Free Parking, Bar/Lounge, Free Wi-fi, Evening entertainment, Gift shop, Pet Friendly, Air conditioning, Kitchenette, Refrigerator, Private balcony, Microwave
  • Rating: 4.5 stars
3. Monmouth Historic Inn and Gardens
Management/TripAdvisor
1358 John A Quitman Blvd, Natchez, MS 39120, USA
Management/TripAdvisor
The Monmouth Historic Inn is a National Historic Landmark that was built in Natchez in 1818 and is a member of Southern Living’s Hotel Collection. This antebellum mansion sits on 26 beautiful acres with lovingly manicured gardens with statues, walking paths, and a charming gazebo. Each of the guest rooms has unique, old-fashioned furniture with lovely paintings and portraits, four-poster canopy beds, and its own color scheme. Quaint antiques are found throughout the property and you’ll find yourself on the veranda with a mint julep in hand in no time.

  • Address: 1358 John A Quitman Blvd, Natchez, MS 39120
  • Price: From $215/night
  • Amenities: Free Parking, Free continental breakfast, Free Wi-fi, Fishing, Meeting rooms, Banquet room, Massage, Air conditioning, Safe, Wake-up service, Housekeeping, Bottled water, Flatscreen TV
  • Rating: 4.5 stars

Best Hotel Pools In Mississippi

Mississippi can get rather humid during the warmer months and you’ll want to take a refreshing dip in a cool swimming pool for a refreshing respite. While any pool is welcome on a hot summer day, having a big, luxurious pool adds extra fun and comfort. Here are two top hotels in Mississippi with the best pools in which you’ll be glad to cool off.

4. Beau Rivage Resort & Casino Biloxi
Hotels.com/Google
875 Beach Blvd, Biloxi, MS 39530, USA
Management/Google
There are shaded gazebos and the outdoor swimming pool has lots of room in which to swim at the Beau Rivage Resort & Casino at Biloxi Beach. Clear, cool waters are surrounded by an ample supply of lounge chairs. If you would prefer to tan away from the pool, there’s a deck that overlooks the Gulf of Mexico. There’s even a beautifully decorated set of indoor hot tubs to soak in. Whatever your preferences, you’re sure to find what you need at this lovely resort that is within sight of the historic Biloxi Lighthouse.

  • Address: 875 Beach Blvd, Biloxi, MS 39530
  • Price: From $189/night
  • Amenities: Free Parking, Pool, Bar/lounge, Game room, Wifi, Fitness center, Casino, Pet friendly, Blackout curtains, Desk, Safe, Cable TV, Air conditioning, Housekeeping, Coffee maker, Ocean view
  • Rating: 4.5 stars
5. IP Casino Resort Spa
Kim Stovall/Google
850 Bayview Ave, Biloxi, MS 39530, USA
Robin Johnson/Google
The IP Casino Resort Spa boasts a huge rooftop pool with a massive poolside TV where you can float on a tube or raft and soak in a show. Within steps of the pool is a whirlpool jacuzzi with ample room for several people. The hotel features views of islands that sit in Biloxi Bay and it’s less than a five-minute drive from MGM Park and Biloxi Bay Bridge in the Gulfport area.

  • Address: 850 Bayview Ave, Biloxi, MS 39530
  • Price: From $96/night
  • Amenities: Free Parking, Pool, Bar/lounge, Game room, Wifi, Fitness center, Casino, Business center, Air conditioning, Safe, Refrigerator, Room service, VIP room facilities, Flatscreen TV
  • Rating: 4.0 stars

Best Luxury Hotels In Mississippi

When you’re ready to be pampered and stay in style with top-quality service and amenities when the price is no object, then you’ll want the most luxurious and beautiful hotels and resorts in Mississippi. This state is known for offering quaint Southern charm and opulent accommodations for well-heeled visitors that expect the very best. These two options are sure to give you just that.

6. Fairview Inn
Management/TripAdvisor
734 Fairview St, Jackson, MS 39202, USA
Management/TripAdvisor
The Fairview Inn is a 4-star hotel in Jackson that is gorgeously detailed with old-fashioned style. This is a historic Colonial Revival Mansion that was built in 1908 and is filled to the brim with astonishingly beautiful details everywhere you look. Rest in front of the fireplace on quaint furnishings and melt into the soft, luxurious beds after a fine meal and craft cocktails at the Library Lounge. There are relaxing and rejuvenating spa treatments and massages available to soothe you.

  • Address: 734 Fairview St, Jackson, MS 39202
  • Price: From $279/night
  • Amenities: Free Parking, Fitness center, Highchairs available, Business center, Free wi-fi, Bar/lounge, Pet friendly, Conference facilities, Bathrobes, Desk, Housekeeping, Flatscreen TV, Air conditioning, Fireplace, Coffee maker, Walk-in shower
  • Rating: 4.5 stars

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7. Duff Green Mansion
Management/TripAdvisor
1114 1st E St, Vicksburg, MS 39183, USA
Management/TripAdvisor
One might not expect a bed and breakfast to be so opulent, but The Duff Green Mansion is the epitome of luxury and Southern hospitality. Luxuriously appointed dining and sitting areas will have you mesmerized by the fine details. Enjoy a three-course Southern breakfast in the morning followed by a tour of the elegant and historic mansion led by a costumed guide. There are several quiet outdoor spaces to relax and there is so much history to explore in this mansion and all over Vicksburg.

  • Address: 1114 First East St, Vicksburg, MS 39183
  • Price: From $174/night
  • Amenities: Free parking, Pool, Bicycle rental, Highchairs available, Free wi-fi, Free breakfast, Game room, Banquet room, Air conditioning, Seating area, Coffee maker, Flatscreen TV, Housekeeping, Refrigerator
  • Rating: 4.5 stars
8. Chancellor’s House
Management/TripAdvisor
425 S Lamar Blvd, Oxford, MS 38655, USA
Hotels.com/Google
The charming small town of Oxford is where you’ll find the gorgeous Chancellor’s House. This luxury hotel has a 24-hour front desk so you can check in any time you like. The elegant decor with marble floors, crystal chandeliers, and beautiful art and furnishings make this a quality accommodation where you can rest after visiting local historic locations and the wide selection of quality Italian restaurants that call the lovely town of Oxford home.

  • Address: 425 S Lamar Blvd, Oxford, MS 38655
  • Price: From $139/night
  • Amenities: Bar/Lounge, Patio, Pet-friendly, Free wi-fi, Evening entertainment, Children's activities, Business center, Blackout curtains, Air conditioning, Housekeeping, Coffee maker, Bathrobes, Desk, Room service, Flatscreen TV
  • Rating: 4.5 stars

Best Boutique Hotels In Mississippi

Looking for a mixture of style, charm, uniqueness, and luxury? Look no further! There is a vast array of wonderful boutique hotels in Mississippi that will amaze and comfort you. Get a mix of historical charm, modern tech, and quality service at either of these distinctive offerings.

9. Graduate Oxford
Daniel Antonio Tercero Hernandez/Google
400 N Lamar Blvd, Oxford, MS 38655, USA
Management/TripAdvisor
This hip and stylish hotel in downtown Oxford is a real gem. The Graduate Oxford is filled with an intriguing and inventive style that mixes retro with trendy. Seersucker sofas and vintage books and magazines are in the lobby and you’ll find live blues music or quality cocktails at The Coop terrace lounge and the Cabin 82 bar which are both on-site. It’s within walking distance of the historic downtown district and makes for a memorable getaway.

  • Address: 400 N Lamar Blvd, Oxford, MS 38655
  • Price: From $164/night
  • Amenities: Free parking, Fitness center, Children's activities, Meeting rooms, Free wi-fi, Bar/lounge, Pet-friendly, Rooftop terrace, Air conditioning, Flatscreen TV, Refrigerator
  • Rating: 4.5 stars
10. Travelers Hotel
Hotels.com/Google
212 3rd St, Clarksdale, MS 38614, USA
stormville/TripAdvisor
The Travelers Hotel is an artist-run boutique hotel in Clarksdale with local art adorning the walls, exceptionally friendly staff, and a community feel regardless of where you’re from. There’s a community kitchen where guests can cook meals and the staff is happy to advise of nearby attractions and activities. It’s just around the corner from the Delta Blues Museum and within walking distance of several quaint and delicious eateries.

  • Address: 212 3rd St, Clarksdale, MS 38614
  • Price: From $141/night
  • Amenities: Free parking, Free Wi-fi, Meeting rooms, Bar/lounge, Air conditioning
  • Rating: 5.0 stars

Best Beach Resorts In Mississippi

With several miles of gulf coast beach available mere minutes from the Gulfport-Biloxi International Airport, it’s no surprise that you’ll find some wonderful beachfront resorts where you can stay after taking advantage of nearby boat rentals, golf courses, and fun on the beach. Here are two fun-filled options sure to provide you with great activities and restful sleep.

11. Margaritaville Resort
Hotelbeds/Google
195 Beach Blvd, Biloxi, MS 39530, USA
Doug Austin/Google
The Margaritaville Resort is nearly an amusement park with all the fun things to do. There’s a water park, carnival rides, a swim-up bar, three on-site restaurants, five bars, an arcade, a bowling alley, a rock climbing wall, VR attractions, and much more. If that’s not enough fun and food, you’re right next to a marina and Bubba Gump Shrimp Co. Plus, the rooms are quite clean and comfy.

  • Address: 195 Beach Blvd, Biloxi, MS 39530
  • Price: From $134/night
  • Amenities: Free parking, Pool, Free Wi-fi, Bar/lounge, Water park, Fitness center, Game room, Children's TV, Blackout curtains, Desk, Interconnected rooms available, Cable TV, Air conditioning, Housekeeping, Coffee maker, Ocean view
  • Rating: 4.0 stars
12. Hard Rock Hotel & Casino Biloxi
Paul Bodenhamer/Google
777 Beach Blvd, Biloxi, MS 39530, USA
Gregory and Patricia Bailey/Google
There are Hard Rock Hotels and Casinos all over the world, and for good reason. Music lovers flock here to see instruments, clothing, and other items that belong to world-famous musicians and to see some of them perform as well. Each one has several excellent restaurants, bars, and shops, and the one in Biloxi is no different. The rooms have a cool rock-and-roll decor and the entertainment and amenities make this beach resort in Mississippi a bucket list stay.

  • Address: 777 Beach Blvd., Biloxi, MS 39530
  • Price: From $129/night
  • Amenities: Free parking, Pool, Free Wi-fi, Bar/lounge, Game room, Fitness center, Casino, Pet-friendly, Air conditioning, Room service, Minibar, Housekeeping, Safe, Flatscreen TV
  • Rating: 4.0 stars

These are the nicest hotels in Mississippi and any one of them will make an excellent stay. Have you stayed at any of these locations? If so, let us know about your experiences in the comments. If you’re looking for some quality accommodations that won’t break the bank, take a look at some more of the best hotels in Mississippi.

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More to Explore

Best Hotels & Resorts In Mississippi

William Suphan | March 15, 2023

What are the best hotels for couples in Mississippi?

The best hotels for couples in Mississippi include:

  • The Devereaux Shields House. This romantic bed and breakfast hosts an annual Date Night Escape made especially for couples with a horse-drawn carriage ride, wine and fruit, a dining card, and breakfast.
  • The Dunleith Historic Inn. There are 40 acres of lovely landscaping as well as an old carriage house and a Castle Restaurant. It’s perfect for a romantic getaway.
  • Bethany Guest House. This charming bed and breakfast in Booneville is quiet and intimate and in the morning, you’ll be served an authentic European breakfast.

Learn more about the best hotels for couples in Mississippi.

What are the best kid-friendly hotels for families in Mississippi?

The best kid-friendly hotels for families in Mississippi include:

  • Castaway Key Beach House in Jackson County. The whole family can play and relax on their own private beach and enjoy a firepit, kayaks, crab pots, and more.
  • Spacious Laurel Home in Laurel. This open, bright, and roomy house in a historic neighborhood is a great place to get away from the busy city with your family.
  • Vintage Cottage in Oxford. This charming, old-fashioned cottage has manicured gardens, a huge deck with patio furniture, and three king-sized bedrooms to make room for everyone.

Find out more about the best kid-friendly hotels for families in Mississippi.

What are some historic hotels in Mississippi?

Historic hotels in Mississippi include:

  • The Corners Mansion Inn in Vicksburg. This place was built in the 1800s and is full of antique furniture, historic photographs, old books, and gorgeous decor.
  • Thompson House in Leland. This historic mansion rests on the banks of Deer Creek and has four poster beds and serene views of the garden and creek.
  • Andover Bed and Breakfast in Olive Branch. This was once a plantation and it still contains some of the original furniture and paintings. There are five ornate rooms to choose from.

Discover more about historic hotels in Mississippi.

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